Biomedical Engineering

Group Picture

Postdoctoral Fellows

 

Jian Du
Assistant Research Scientist

 

Research Interests:
The overall objective of my interests is to merge three lines of research that have independently shown promise for advancing tissue engineering endeavors, specifically biomaterial scaffolds, glycosylation engineering, and stem cell research

Education:
Liaoning University, China, B.S.(2000) Chemical Engineering
Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Ph.D. (2005) Applied Chemistry

 

   

Rahul Bhattacharya
Postdoctoral Felllow

Research Interests:
Synthetic Carbohydrate Chemistry
Short chain fatty acid-modified hexosamine-core analogs and their biological properties as part of anti cancer drug development
Nucleoside chemistry

Education:
Burdwan University, West Bengal, India, B.S. (1999), Chemistry with Honors
Jadavpur University, Kolkata ,West Bengal, India, M.S. (2001), Chemistry: Organic Chemistry specialization
Indian Institute of Technology, Kharagpur-India, Ph.D. (2008), Chemistry


Laura Alberch
Postdoctoral Fellow

Research Interests:
-Synthesis of novel carbohydrate analogs to increase their metabolic
 uptake by cells as promising anti-cancer drug candidates.
-Attachment of azide bearing sugars to PEG coated soft nanoparticles for drug delivery.
Education:
The University of Manchester (2002), BSc, MChem
Purdue University, Ph.D. (2011), Chemistry

   
   
   

 

Graduate Students

Freddy

 

Freddy Espinoza
Graduate Student

Research Interests:
My research goal is to design next-generation sugar analogs that build upon the beneficial traits of our existing prodrugs. My doctoral research is driven by my interest in rational drug design with in-vitro testing, specifically involving cancer glycosylation and glycobiology, and in-silico modeling of ligand-protein interactions. My research focus has three aims: to improve the potency, bioavailability, and specificity of our laboratory's sugar analogue prodrugs to malignant tumor cells. I collaborate with researchers in medicinal chemistry, nanoparticle technology, and computational chemistry to accomplish the aims of my research.
Education:
Massachusetts Institute of Technology (MIT), S.B. (2008), Chemical Engineering

 

   

 

 

 

Christopher Saeui
BME Rotating Graduate Student

Research Interests:
Education:

 

 

 

 

 

mohit

 

Mohit Philip Mathew
Graduate Student

Research Interests:

Probing the effect of glycosylation on activity and behavior of cells using metabolic oligosaccharide engineering. 1) Studying the effect of glycosylation on intracellular esterase activity using unnatural sugar analogs. 2) Searching for specific targets of glycosylation using wound healing assays and click chemistry. 3) Investigating the differences in uptake efficiency between liposomal delivery methods and butyration of sugar analogs. 4) Elucidating the dynamics of extracellular inactivation of butyrated sugar analogs in serum.

Education:

B.E. Biotechnology Manipal Institute of Technology, Manipal, India

 

 

 

 

 
Research Technicians
   

 

Elaine Tan
Research Technologist

 

Research Interests:
Glycoengineering and cancer treatment:
-Studying apoptotic pathway induced by unnatural sugar analogs in cancer cells.
-Understanding how glycoengineering affects intracellular esterases.

Education:
Johns Hopkins University, M.S. (2010), Biomedical Engineering

 

 
Undergraduate Students
Hyo Jun Kim
Undergraduate Student
   
 
Jun
Jun Huang
Undergraduate Student
   

Margaret Chow

Undergraduate Student


   

 

Jiarui (Jerry) Wang
Undergraduate Student class of 2015

 

 

Brian Choi
Undergraduate Student