Publications

B. Book Chapters and Review Articles:
B1. Yarema, K.J., & Essigmann, J.M. (1995) Evaluation of the genetic effects of defined DNA lesions formed by DNA damaging agents.  Methods: A Companion to Methods in Enzymology, 7, 133-146. 7 citations (Google)
B2. Yarema, K.J. (1995) Comparative toxicities and mutagenicities of platinum anticancer drugs. Drug Information Journal, 29, 1633S-1644S.
B3. Mahal, L.K., Yarema, K.J., Lemieux, G.A., & Bertozzi, C.R.  (1999)  Chemical approaches to glycobiology:  Engineering cell surface sialic acids for tumor targeting  In Sialobiology and Other Novel Forms of Glycosylation (Inoue, Y., Lee, Y.C. & Troy II, F.A, Eds.)  Gakushin Publishing Company, Osaka, Japan. pp 273-280.
B4. Yarema, K.J. & Bertozzi, C.R. (1998) Chemical approaches to glycobiology and emerging carbohydrate-based therapeutic agents.  Current Opinion in Chemical Biology, 2, 49-61. 96 citations (95 Google)
B5. Jacobs, C.L., Yarema, K.J., Mahal, L.K., Nauman, D.A., Charters, N., & Bertozzi, C.R. (2000)  Metabolic labeling of glycoproteins with chemical tags through unnatural sialic acid biosynthesis. Methods in Enzymology, 327, 260-275. 33 citations (36 Google)
B6. Yarema, K.J. & Bertozzi, C.R. (2001) Characterizing glycosylation pathways. Genome Biology, 2, REVIEWS0004-0010. 17 citations (36 Google)
B7. Yarema, K.J. (2001) New directions in carbohydrate engineering: A metabolic substrate-based approach to modify the cell surface display of sialic acids. Biotechniques, 31, 384-393. 9 citations (12 Google)
B8.  Yarema, K.J. (2002) A metabolic substrate-based approach to engineering new chemical reactivity into cellular sialoglycoconjugates.  In Cell Engineering, Volume 3: Glycosylation (M. Al-Rubeai, Ed.) Kluwer Academic Publishers, Dordrecht. pp 171-196.
B9. Tong, L., Baskaran, G., Jones, M. B., Rhee, J.K., & Yarema, K.J. (2003) Glycosylation changes as markers for the diagnosis and treatment of human disease. In Biotechnology and Genetic Engineering Reviews, Volume 20. (S.E. Harding, ed.) Intercept, Ltd., Andover, Hampshire, UK. pp.199-246. 9 citations (10 Google)
B10. Yarema, K.J., (2005) Editor of Handbook of Carbohydrate Engineering. CRC Press (Taylor & Francis Group), Boca Raton, FL, USA, (29 chapters, 904 pages).
B11. Chen, H., Wang, Z., Sun, Z., Kim, E.K., & Yarema, K.J., (2005) Chapter 1. Mammalian glycosylation: An overview of carbohydrate biosynthesis. In Handbook of Carbohydrate Engineering. (K.J. Yarema, ed.) CRC Press (Taylor & Francis Group), Boca Raton, FL, USA, pp 1-48.
B12. Chen, H., Wang, Z., Sun, Z., Kim, E.K., & Yarema, K.J., (2005) Chapter 1. Mammalian glycosylation: An overview of carbohydrate biosynthesis. In Handbook of Carbohydrate Engineering. (K.J. Yarema, ed.) CRC Press (Taylor & Francis Group), Boca Raton, FL, USA, pp 1-48. 3 citations (10 Google)
B13. Murrell, M.P., Yarema, K.J., & Levchenko, A., (2005) Chapter 8. Computational modeling in glycosylation. In Handbook of Carbohydrate Engineering. (K.J. Yarema, ed.) CRC Press (Taylor & Francis Group), Boca Raton, FL, USA, pp 247-287.
B14. Sampathkumar, S.-G. & Yarema, K.J. (2005). Targeting cancer cells with dendrimers. Chemistry & Biology, 12, 5-6. 26 citations (28 Google)
B15. Yarema, K.J. & Sun, Z. (2005) A Photochemical snapshot of CD22 binding. Nature Chemical Biology, 1, 69-70. 2 citations (2 Google)
B16. Campbell C.T. & Yarema, K.J. (2005) Large-scale approaches for glycobiology. Genome Biology, 6, 236-244. 24 citations (31 Google)
B17. Sampathkumar, S.-G. & Yarema, K.J. (2007) Chapter 1: Dendrimers in cancer treatment & diagnosis. In Nanotechnologies for the Lifesciences - Vol. 06: Nanomaterials for Cancer Diagnosis and Therapy (C. S. S. R. Kumar, ed.) John Wiley & Sons, Hoboken, NJ, pp 1-47.
B18. Sampathkumar, S.-G., Campbell, C.T., Weier, C., & Yarema, K.J. (2006) Short-chain fatty acid-hexosamine cancer prodrugs: The sugar matters! Drugs of the Future, 31,1099-1116. 7 citations (9 Google)
B19. Aich, U., & Yarema, K.J. (2008) Chapter 10.3 - Non-natural sugar analogues: Chemical probes for metabolic oligosaccharide engineering. In Glycoscience – Chemistry and Chemical Biology, 2nd Edition, Kondou, H., & Thiem, J., Eds., Springer-Verlag, Heidelberg, Germany, pp 2133-2190.
B20. Elmouelhi, N., & Yarema, K.J. (2008) Chapter 2 - Building on what nature gave us: Engineering cell glycosylation pathways. In Biotechnology and Bioengineering Research Trends. Flynne, W. G., Ed., Nova Publishers, Hauppauge, NY, pp 37-73.
B21. Meledeo, M.A., & Yarema, K.J. (2008) Glycan biosynthesis and glycosylation in mammals. In Wiley Encyclopedia of Chemical Biology (Begley, T, Ed.) Published online at 10.1002/9780470048672.wecb190, 1-16.
B22. Atukorale, P.U., Choi, S.S., Aich, U., Campbell, C.T., Meledeo, M.A., & Yarema, K.J. (2009) Chemical biology of cell surface oligosaccharides. In Protein Targeting with Small Molecules, Osada, H., Ed., John Wiley & Sons pp 189-221.
B23. Aich, U., & Yarema, K. J. (2009) Chapter 1 - Glycobiology & Immunology. In Carbohydrate-Based Vaccines in "The Wiley Series in Drug Discovery and Development" (Guo, Z., & Boons, G.-J., Eds.) John Wiley & Sons, Hoboken, NJ, pp 1-53.
B24. Meledeo, M.A., Paruchuri, Venkata D.P., Du, J., Wang, Z., & Yarema, K.J. (2011) Chapter 1. Mammalian glycan biosynthesis: Building a template for biological recognition. In Carbohydrate Recognition: Biological Problems, Methods, and Applications (Wang, B., & Boons, G.-J., Eds.) John Wiley & Sons, Hoboken, NJ, pp 1-32.
B25. Tan, E., Du., J., Almaraz, R., & Yarema, K.J. (2010) Experimental design considerations for in vitro non-natural glycan display via metabolic oligosaccharide engineering. Current Protocols in Chemical Biology, 2, 181-204.
B26. Du., J., Almaraz, R., Tan, E., & Yarema, K.J. (2011) Metabolic glycoengineering of sialic acids. In Sialobiology eBook (Tiralongo, J., Ed.) Bentham Science Publishers (invited article, in press)
B27. Almaraz, R.T., Mathew, M.P., Tan, E., & Yarema, K.J. (2011) Metabolic oligosaccharide engineering: Implications for selectin-mediated adhesion and leukocyte extravasation. Annals of Biomedical Engineering, (invited article for the Glycomechanics Special Issue, in press).

C. Peer-reviewed Abstracts and Poster Presentations:
C1. Paige, L.A., Yarema, K.J., Rink, S., Essigmann, J.M., & Croy, R.G. (1995) Programmable therapeutics: A strategy that can selectively direct the cytotoxic effects of anticancer compounds to tumor cells. Massachusetts Biotechnology Council 4th Annual Symposium, at MIT, Cambridge, MA.
C2. Yarema, K.J., Mahal, L.K., & Bertozzi, C.R. (1996) Engineering novel cell surface chemistry using the pathways for oligosaccharide biosynthesis.  Glycobiology, 6, 754.
C3. Yarema, K.J., Mahal. L.K., & Bertozzi, C.R. (1997) Applications of unnatural oligosaccharide biosynthesis to selective drug delivery.  213th ACS National Meeting at San Francisco, CA, April 13-17, 1997.
C4.  Yarema, K.J., Goon, S., & Bertozzi, C.R. (2000)  Metabolic selection of cells with glycosylation defects found in human disease.  International Carbohydrate Symposium at Hamburg, Germany, August 26-29, 2000.
C5. Yarema, K.J., Goon, S. & Bertozzi, C.R. (2001) Metabolic selection of cell with glycosylation defects found in human disease. UCBerkeley 2001 Molecular and Cell Biology Retreat at Asilomar, California, January, 2001.
C6. Yarema, K.J., Goon, S., & Bertozzi, C.R. (2001) Metabolic selection of cells with glycosylation defects found in human disease. 4th Annual San Diego Glycobiology Symposium at San Diego, CA, January 12 and 13, 2001.
C7. Luchansky, S.J., Yarema, K.J., & Bertozzi, C.R. (2002) Efforts towards elucidating the chemical mechanism and role of the GlcNAc 2-epimerase in the cell.  Society for Glycobiology 2002 National Meeting, Boston, MA, November 10-12, 2002 (Glycobiology 12, 690).
C8. Chen, H., Jones, M.B., Teng, H., Rhee, J.K., Baskaran, G., Lahar, N., & Yarema, K.J., (2002)   Evaluation of the metabolic flux of acetylated ManNAc analogs through the sialic acid biosynthetic pathway.  Society for Glycobiology 2002 National Meeting, Boston, MA, November 10-12, 2002 (Glycobiology 12, 700).
C9. Sampathkumar, S.G., Jones, M.B., & Yarema, K.J. (2003) Engineering of cell surface sialic acids: Synthesis of analogs of 2-N-acylamino-2-deoxy-a,b-D-mannopyranose and studies on their efficacy of cellular uptake and toxicity.  The 23rd Gordon Research Conference on Carbohydrates, Tilton, NH, June 22-27, 2003.
C10. Sampathkumar, S.G., Jones, M.B., & Yarema, K.J. (2003) Engineering of cell surface sialic acids: Synthesis of analogs of 2-N-acylamido-2-deoxy-a,b-D-mannopyranose and studies on their efficacy of uptake and toxicity. The 226th ACS National Meeting, New York, NY, September 7-11, 2003.
C11. Kim, E.J., Rhee, J.K., Sampathkumar, S.-G., Jones, M.B., Baskaran, G. & Yarema, K.J. (2003) Characterization of the apoptotic effects of N-acetylmannosamine (ManNAc) analogs in Jurkat (human T-lymphoma-derived) cells. Society for Glycobiology 2003 National Meeting, San Diego, CA, December 3-6, 2003 (Glycobiology 13, 856).
C12. Chen, H., Sun, Z., & Yarema, K.J. (2003) Establishing a correlation between mutant forms of GNE found in HIBM and the expression of neurotrophic factors.  Society for Glycobiology 2003 National Meeting, San Diego, CA, December 3-6, 2003. (Glycobiology 13, 901).
C13. Sampathkumar, S.-G., Jones, M.B., & Yarema, K.J.  (2003) Engineering of cell surface sialic acid. Synthesis of analogs of 2-N-Acylamino-2-deoxy-α,β-D-mannopyranose and studies on their efficacy of uptake and toxicity. Society for Glycobiology 2003 National Meeting, San Diego, CA, December 3-6, 2003 (Glycobiology 13, 891).
C14. Sampathkumar, S.-G., Jones, M.B., & Yarema, K.J. (2004) Metabolic substrate based engineering of cell surface sialic acids: synthesis of peracylated N-acyl-D-mannosamine analogs containing pendant thiol groups and studies on their efficacy of cellular uptake and toxicity. The 228th ACS National Meeting, Philadelphia, PA August 22-26, 2004.
C15. Sampathkumar, S.G., Jones, M.B., & Yarema, K.J. (2004) Substrate based metabolic engineering of cell surface sialic acids: Synthesis and applications of novel N-acylmannosamine analogs possessing pendant thiol groups as metabolic precursors. Society for Glycobiology 2004 National Meeting, Honolulu, HI, November 17-20, 2004. Glycobiology, 14, abstract 126.
C16. Li, A., Wang, Z., Murrell, M.P., Cameron, B., Baskaran, G., Stamatos, N.M., Mao, H.-Q., & Yarema, K.J. (2004) The sialic acid biology of human stem cells: Basic steps towards the characterization and manipulation of glycosylation to control their differentiation and proliferation. Society for Glycobiology 2004 National Meeting, Honolulu, HI, November 17-20, 2004. Glycobiology, 14, abstract 347.
C17. Jones, M.B., Sampathkumar, S.-G., & Yarema, K.J.  (2004) Monosaccharides provide an efficient delivery method for butyrate, a short chain fatty acid (SCFA) with anti-cancer activity. Society for Glycobiology 2004 National Meeting, Honolulu, HI, November 17-20, 2004. Glycobiology (2004) 14: abstract 426.
C18. Chen, H., Hinderlich, S. & Yarema, K.J.  (2004) Recombinant GNE alters the expression of proteins important for muscle functions and provides insights into the cellular basis of HIBM. Society for Glycobiology 2004 National Meeting, Honolulu, HI, November 17-20, 2004. Glycobiology (2004) 14: abstract 440.
C19. Wang, Z., Sun, Z., Chen, H., Hinderlich, S. & Yarema, K.J.  (2004) Feedback control mechanisms, not the potential catalytic epimerization activity of GNE, determines bulk metabolic flux through the sialic acid biosynthetic pathway. Society for Glycobiology 2004 National Meeting, Honolulu, HI, November 17-20, 2004. Glycobiology, 14: abstract 441.
C20. Salama, I., Hinderlich, S., Shlomai, Z., Eisenberg, I., Krause, S., Yarema, K., Argov, Z., Reutter, W., Lochmuller, H., Dabby, R., Sadeh, M., Ben-Bassat, H., & Mitrani-Rosenbaum, S. (2004) Biochemical characterization of myoblasts from Hereditary Inclusion Body myopathy patients with various mutations in GNE. Society for Glycobiology 2004 National Meeting, Honolulu, HI, November 17-20, 2004. Glycobiology, 14: abstract 528.
C21. Sampathkumar, S.-G., Jones, M.B., & Yarema, K.J. (2005) Novel method for the expression of thiols on cell surface carbohydrates with applications to tissue engineering, Gordon Research Conference on Carbohydrates, Tilton School, Tilton, New Hampshire, June 19-24, 2005.
C22. Sampathkumar, S.-G., Jones, M.B., Hida, K., Gomutputra, P., Sheh, T. H., & Yarema, K.J. (2005) Design and synthesis of novel SCFA carbohydrate hybrids with anti-cancer properties. American Chemical Society Meeting & Exposition, Washington, DC, USA, August 28 – September 1, 2005.
C23. Yarema, K.J. (2005) Development of therapeutic applications for N-acetylmannosamine (ManNAc) analogues used for the manipulation of sialic acid metabolism. GLYCO XVIII: The International Symposium on Glycoconjugates. Firenze, Italy, September 4-9, 2005. Glycoconjug. J., 4-6, 188.
C24. Yarema, K.J. (2005) Connections between apoptosis and sialic acid metabolism: Application to new cancer therapies. GLYCO XVIII: The International Symposium on Glycoconjugates. Firenze, Italy, September 4-9, 2005. Glycoconjug. J., 4-6, 366.
C25. Sampathkumar, S.-G., Li, A.V., Jones, M.B., Hida, K., & Yarema, K.J. (2005) Metabolic engineering novel adhesive properties into cell surface carbohydrates. Biomedical Engineering Society National Meeting, Baltimore, MD, USA, September 28 - October 1, 2005 (Abstract # 767).
C26. Sampathkumar, S.-G., Campbell, C.T., Li, A.V., Jones, M.B., Sun, Z., Sarje, A., Thakor, N.V. & Yarema, K.J. (2005) Modulation of cell adhesion or attachment using sialic acid engineering methods. Society for Glycobiology 2005 National Meeting, Boston, MA, November 9-13, 2005. Glycobiology, 15: abstract 97 (p. 1210).
C27. Wang, Z., Sun, Z., & Yarema, K.J. (2005) GNE is involved in cell growth via modulation of ganglioside metabolism. Society for Glycobiology 2005 National Meeting, Boston, MA, November 9-13, 2005. Glycobiology, 15: abstract 245 (p. 1248).
C28. Sampathkumar, S.-G., Jones, M.B., Meledeo, M.A., Hida, K., Sheh, A.H., Gomutputra, P., & Yarema, K.J. (2005) Carbohydrate-based small molecules as anti-cancer drugs: Short chain fatty acid-hexosamine hybrids. Society for Glycobiology 2005 National Meeting, Boston, MA, November 9-13, 2005. Glycobiology, 15: abstract 250 (p. 1249).
C29. Sampathkumar, S.-G., Li, A.V., Jones, M.B., Atukorale, P.U., Campbell, C.T., & Yarema, K.J. (2006) A carbohydrate based small molecule induces b-catenin accumulation and neural differentiation in human stem cells. Keystone Symposia on Wnt and b-catenin signaling in development and disease, Snowbird, UT, April 7-12, 2006.
C30. Sampathkumar, S.-G., Sarje, A., Li, A.V., Jones, M.B., Sun, Z., Atukorale, P.U., & Yarema, K.J. (2006) Metabolic substrate-based oligosaccharide engineering: A new tool for tissue engineering and stem cell biology. World Congress on Tissue Engineering and Regenerative Medicine, Pittsburgh, PA, April 25-27, 2006.
C31. Loo, Y., Sampathkumar, S.-G., Atukorale, P.U., Yarema, K.J., & Leong, K.W. (2006) Engineering of cell surface sialic acids for polymeric gene delivery. 9th Annual Meeting of the American Society for Gene Therapy, Baltimore, MD, May 31-June 4, 2006.
C32. Campbell, C.T., Sampathkumar, S.-G., Wen, M., Wang, J., Weier, C., Yarema, K. (2006) Sialic acid engineering for modifying invasiveness of breast cancer. The Susan G. Komen Foundation's ninth annual Mission Conference, Washington, D.C., June 11 - 13, 2006.
C33. Sampathkumar, S.-G., Campbell, C.T., Jones, M.B., Meledeo, M.A., Fu, J., Hida, K., Sheh, A., Gomatputra, P., Choi, S.S., Wang, J., Wen, M., Weier, C.A., David, M., Hanes, J., & Yarema, K.J. (2006) Carbohydrate-n-butyrate hybrid prodrugs: Sugar-dependent anti-cancer activity. XXIIIrd International Carbohydrate Symposium, Whistler, British Columbia, Canada, July 23-28, 2006.
C34. Atukorale, P.U., Sampathkumar, S.-G., Li, A.V., Jones, M.B., Sarje, A., Christopherson, G., Sun, Z., Lewis, L., Mao, H.-Q., & Yarema, K.J. (2006) Metabolic installation of thiols into sialic acid modulates adhesion and stem cell biology. XXIIIrd International Carbohydrate Symposium, Whistler, British Columbia, Canada, July 23-28, 2006.
C35. Wang, Z., Sun, Z, & Yarema, K.J. (2006) Tissue-specific roles for GNE in cell growth. Society for Glycobiology 2006 National Meeting, Los Angeles, CA, November 15-18, 2006. Glycobiology, 16: abstract 69 (p. 1117).
C36. Sampathkumar, S.-G., Campbell, C.T., Meledeo, M.A., Choi, S.S., David, M., Fu, J., Hanes, J., & Yarema, K.J. (2006) Carbohydrate-short chain fatty acid hybrids as anti-cancer prodrugs: The sugar matters. Society for Glycobiology 2006 National Meeting, Los Angeles, CA, November 15-18, 2006. Glycobiology, 16: abstract 262 (p. 1154).
C37. Atukorale, P.U., Sampathkumar, S.-G., Jones, M.B., Li, A.V., & Yarema, K.J. (2006) Neural differentiation of human stem cells via metabolic sialic acid engineering. Society for Glycobiology 2006 National Meeting, Los Angeles, CA, November 15-18, 2006. Glycobiology, 16: abstract 231 (p. 1148).
C38. Campbell, C.T., Zaidi, H., Fu, J., Weier, C., Sampathkumar, S.-G., Li, K.W., Tyler, B.M., Jones, M.B., Hanes, J., Yarema, K.J., and Brem, J. Treatment of CNS tumors with N-acetylmannosamine tetrabutyrate, 2007 American Association of Neurological Surgeons Annual Meeting, Washington, District of Columbia, April 14-19, 2007.
C39. Atukorale, P.U., Sampathkumar, S.-G., Jones, M.B., Li, A.V., & Yarema, K.J. (2007) Neural differentiation of human stem cells via metabolic sialic acid engineering. The Institute for NanoBiotechnology Spring Symposium, Baltimore, MD, April 27, 2007.
C40. Aich, U., Campbell, C.T., Sampathkumar, S.-G., Weier, C. Choi, S. S., Meledeo, M.A. Contijoch, F., & Yarema, K. J. (2007) Regiospecific attachment of short chain fatty acid (SCFA) groups to ‘core’ amino sugars decouples metabolic flux from toxicity. 2007 Midwest Carbohydrate and Glycobiology Symposium, Ohio State University, Columbus, OH, October 5-6, 2007.
C41. Aich, U., Campbell, C.T., Sampathkumar, S.-G., Weier, C. Choi, S. S., Meledeo, M.A. Contijoch, F., & Yarema, K. J. (2007) Regiospecific attachment of short chain fatty acid (SCFA) groups to ‘core’ amino sugars decouples metabolic flux from toxicity. Society for Glycobiology 2007 National Meeting, Boston, MA, November 11-15, 2007. (Abstract #247)
C42. Campbell, C.T., Elmouelhi, N., Weier, C.A., Meledeo, M.A., Aich, U., Wang, J.J., Wen, M.W., Sampathkumar, S.-G., & Yarema, K.J. (2007) SCFA-Monosaccharide analogs: New tools to deconvolute the influence of HDACi and NF-kB over invasion in metastatic breast cancer cells. Society for Glycobiology 2007 National Meeting, Boston, MA, November 11-15, 2007. (Abstract #224)
C43. Atukorale, P.U., Sampathkumar, S.-G., Che, P.-L., Sarje, A., Aich, U., & Yarema, K.J. (2007) Development of novel tissue engineering technologies: Metabolic engineering of thiol groups into the surface sialic acids of human stem cells. Society for Glycobiology 2007 National Meeting, Boston, MA, November 11-15, 2007. (Abstract #140)
C44. Wang, Z., Sarje, A., Che, P., & Yarema, K.J. Static magnetic fields (SMF) activate signaling networks in human embryonic cells governed by concomitant changes to gangliosides. Society for Glycobiology 2007 National Meeting, Boston, MA, November 11-15, 2007. (Abstract #156)
C45. Atukorale, P.U., Sampathkumar, S.-G., Che, P.-L., Sarje, A., Aich, U., & Yarema, K.J. (2007) Development of novel tissue engineering technologies: Metabolic engineering of thiol groups into the surface sialic acids of human stem cells. Hopkins Brain Science Institute – 2007 Fall Symposium, Baltimore, MD, December 14, 2007. (Presentation #14)
C46. Wang, Z., Sarje, A., Che, P., & Yarema, K.J. Static magnetic fields (SMF) activate signaling networks in human embryonic cells leading to the expression of oligodendrocyte markers. Johns Hopkins Brain Science Institute – 2007 Fall Symposium, Baltimore, MD, December 14, 2007. (Presentation #15)
C47. Aich, U., Campbell, C.T., Sampathkumar, S.-G., Elmouelhi, N., Weier, C.A., Meledeo, M. A, Contijoch, F., & Yarema, K.J. (2008) Design of SCFA-ManNAc hybrid molecules for the selective control of sialic acid biosynthesis and toxicity. Division of Carbohydrate Chemistry, The 235th ACS National Meeting, New Orleans, LA, April 6-10, 2008.
C48. Aich, U., Meledeo, M. A., Fu, J., Hanes, J., & Yarema, K.J. (2008) Encapsulation of SCFA-hexosamine prodrugs in degradable polymers and formulation into nanoparticles for controlled release and cancer targeting. The Institute for NanoBiotechnology Spring Symposium, The Johns Hopkins University, Baltimore, MD, May 2, 2008.
C49. Du, J., Che, P.-L., Wang, Z., Aich, U., & Yarema, K.J. (2008) Electrospun nanofibers enhance glycoengineered cell adhesion. The Institute for NanoBiotechnology Spring Symposium, The Johns Hopkins University, Baltimore, MD, May 2, 2008.
C50. Meledeo, M.A., Elmouelhi, N., Campbell, C.T., & Yarema, K.J. (2008) Differential effects of tri-O-butyl N-acetyl sugar analogs on cancer progression pathways. National Institutes of Health Glycosciences Day, Bethesda, MD, May 9, 2008 (Abstract #1)
C51. Atukorale, P.U., Sampathkumar, S.-G., Che, P.-L., Sarje, A., Aich, U., & Yarema, K.J. (2008) Development of novel tissue engineering technologies: Metabolic engineering of thiol groups into the surface sialic acids of human stem cells. National Institutes of Health Glycosciences Day, Bethesda, MD, May 9, 2008 (Abstract #2)
C52. Aich, U., Campbell, C.T., Sampathkumar, S.-G., Weier, C. Choi, S. S., Meledeo, M.A. Contijoch, F., & Yarema, K. J. (2008) Regiospecific attachment of short chain fatty acid (SCFA) groups to ‘core’ amino sugars decouples metabolic flux from toxicity. National Institutes of Health Glycosciences Day, Bethesda, MD, May 9, 2008 (Abstract #3)
C53. Aich, U., Srinivasa, R., Meledeo, M.A., Khanna, H.S., Campbell, C.T., & Yarema, K.J. (2008) Insights into esterase processing and anti-cancer properties of SCFA-hexosamine analogs obtained through AutoDock modeling. NIH Chemical Biology Symposium, Bethesda, MD, August 16, 2008.
C54. Du, J., Che, P.-L, Wang, Z., Aich, U., Agrawal, R.R., & Yarema, K.J. (2008) Exploiting sialic acid-displayed thiols for tissue engineering. Society for Glycobiology 2008 National Meeting, Dallas, TX, November 12-15, 2008 (v18, p997, Abstract #231).
C55. Meledeo, M. A., Price, K. J., Sheng, M., Xu, N., Aich, U., & Yarema, K.J. (2008) Treatment of a mouse cancer model with 3,4,6-O-Bu3ManNAc: understanding how tri-O-butanoyl ManNAc analogs drive apoptosis. Society for Glycobiology 2008 National Meeting, Dallas, TX, November 12-15, 2008 (v18, p962, Abstract #89).
C56. Aich, U., Srinivasa, R., Meledeo, M. A., Khanna, H. S., Campbell, C. T., & Yarema, K.J. (2008) Insights into esterase processing and anti-cancer properties of SCFA-hexosamine analogs obtained through AutoDock modeling. Society for Glycobiology 2008 National Meeting, Dallas, TX, November 12-15, 2008 (v18, p964, Abstract #98).
C57. Paruchuri, V. D. P., Elmouelhi, N., Aich, U., Meledeo, M. A., Campbell, C. T., & Yarema, K.J. (2008) Hexosamines as scaffolds for drug discovery: Exploration of the cellular effects of acylated ManNAc, GlcNAc, and GalNAc analogs. Society for Glycobiology 2008 National Meeting, Dallas, TX, November 12-15, 2008 (v18, p997, Abstract #230).
C58. Du, J., Che, P.-L., Wang, Z.-Y., Aich, U., & Yarema, K.J. (2009) Electrospun nanofibers enhance glycoengineered cell adhesion. The Institute for NanoBiotechnology Spring Symposium, The Johns Hopkins University, Baltimore, MD, May 2, 2009.
C59. Du, J., Tan, E., Che, P.-L., Wang, Z.-Y., & Yarema, K.J. (2009) Electrospun nanofibers for neural promotion. The Institute for NanoBiotechnology Spring Symposium-Nanoscience for Neuroscience & Neurosurgery, The Johns Hopkins University, Baltimore, MD, May 18, 2009. (Poster #27).
C60. Du, J., & Yarema, K.J. (2009) Exploring stem cell and cancer cell biology with sugar analogs. NIH/FDA Glycoscience Research Day, Bethesda, Maryland, May 28, 2009. (Invited talk).
C61. Du, J., Che, P.-L., Tan, E., Wang, Z.-Y., & Yarema, K.J. (2009) Exploring stem cell biology and tissue engineering with sugar analogs. NIH/FDA Glycoscience Research Day, Bethesda, Maryland, May 28, 2009. (Poster presentation and Abstract #32).
C62. Che, P.-L., Du, J., Tan, E., Wang, Z.-Y., & Yarema, K.J. (2009) Studies on the combined effects of sugar analogs and three dimensional growth substrates in modulating immune and cancer cell behavior. NIH/FDA Glycoscience Research Day, Bethesda, Maryland, May 28, 2009. (Poster presentation and Abstract #19; winner of “Outstanding Poster” award).
C63. Che, P.L., Du, J., Tan, E., Atukorale, P., & Yarema, K.J. (2009) Hexosamines as scaffolds for drug discovery: A combination of sugar analogs and three dimensional growth substrates modulates cancer and embryonic cell behavior. Society for Glycobiology 2009 National Meeting, San Diego, CA, November 12-15, 2009 (v19, p1298-1299, Abstract #38).
C64. Du, J., Che, P.L., Tan, E., Chung, S., Wang, Z.-Y., Meledeo, M.A., & Yarema, K.J. (2009) Hexosamines as scaffolds for drug discovery: Creating uniform embryoid bodies from dissociated Human embryonic cells using metabolic glycoengineering methodology. Society for Glycobiology 2009 National Meeting, San Diego, CA, November 12-15, 2009 (v19, p1304, Abstract #56).
C65. Tan, E., Du, J., & Yarema, K.J. (2009) Thermosensitive polysialic acid hydrogels as bioactive platforms for neural tissue engineering. Society for Glycobiology 2009 National Meeting, San Diego, CA, November 12-15, 2009 (v19, p1362, Abstract #251).
C66. Du, J., Tan, E., Shah, S., Bhattacharya, R., Srinivas, R., & Yarema, K.J. (2010) Metabolic glycoengineering: a new tool for neural tissue engineering. Johns Hopkins Institute for NanoBioTechnology 4th Annual Symposium, Baltimore, MD, April 29, 2010.
C67. Du, J., Tan, E., Shah, S., Bhattacharya, R., & Yarema, K.J. (2010) N-Propanoylmannosamine sugar analogues as small molecules for neural regeneration. NIH Glycoscience Day, Bethesda, MD, May 24, 2010.
C68. Du, J., Tan, E., Shah, S., Bhattacharya, R., Srinivas, R., & Yarema, K.J. (2010) Metabolic glycoengineering: a new tool for neural tissue engineering. NIH Glycoscience Day, Bethesda, MD, May 24, 2010.
C69. Du, J., Shah, S., Tan, E., Srinivas, R., Bhattacharya, R., Qu, Y., Kim, H.J., Mathew, M.P., Espinoza, F.A., & Yarema, K.J. (2010) Metabolic glycoengineering: Exploiting sugars for tissue engineering and regenerative medicine. Johns Hopkins Biomaterials Day, Baltimore, MD, October 29, 2010.
C70. Che, P.L., Du, J., Tan, E., Atukorale, P., & Yarema, K.J. (2010) A combination of sugar analogs and three dimensional growth substrates modulates cancer and embryonic cell behavior. Johns Hopkins Biomaterials Day, Baltimore, MD, October 29, 2010.
C71. Du, J., Tan, E., Shah, S., Bhattacharya, R., Srinivas, R., & Yarema, K.J. (2010) Metabolic glycoengineering: a new tool for neural tissue engineering. Johns Hopkins Biomaterials Day, Baltimore, MD, October 29, 2010.
C72. Shah, S., Du, J., Tan, E., Bhattacharya, R., Srinivas, R., & Yarema, K.J. (2010) Probing the esterase processing of SCFA-hexosamine analogs. Society for Glycobiology 2010 National Meeting, St. Pete Beach, FL November 7-10, 2010 (Abstract #53).
C73. Coburn, J.M., Crist, J, Wo, L., Aich, U., Yarema K.J., & Elisseeff, J.H. (2010) Novel Sugar Analogs for Cartilage Regeneration. TERMIS North America Conference and Expo, Orlando, FL December 5-8, 2010.
C74. Almaraz, R.T., Tian, Y., Bhattarcharya, R., Konstantopoulos, K., Zhang, H., & Yarema, K.J. (2011) Metabolic flux through the sialic acid pathway selectively controls the sialylation and activity of adhesion molecules involved in metastasis. Glycobiology Gordon Research Conference Il Ciocco Hotel and Resort, Lucca (Barga), Italy 8-13 May 2011.
C75. Du, J., Espinoza, F.A., Tan, E., Bhattacharya, R., Shah, S., Mathew, M.P., & Yarema, K.J. (2011) Regulation of cancer cell adhesion via 3D electrospun nanofibrous scaffolds and metabolic oligosaccharide engineering. The Institute for NanoBiotechnology Spring Symposium-Cancer Nanotechnology, The Johns Hopkins University, Baltimore, MD, May 13, 2011.
C76. Shah, S., Tan, E., Bhattacharya, R., & Yarema, K.J. (2011) Investigating the mechanism of apoptotic death of cancer cells treated with SCFA-ManNAc analogs. FDA/NIH Glycoscience Day, Bethesda, MD, June 15, 2011. Winner of a Best Poster Presentation award.
C77. Shah, S., Tan, E., Srinivas, R., Meledeo, M.A., Mathew, M.P., Bhattacharya, R., & Yarema, K.J. (2011) Investigating the esterase processing of butyrated ManNAc analogs. FDA/NIH Glycoscience Day, Bethesda, MD, June 15, 2011.
C78. Espinoza, F.A., Tan, E., Bhattacharya, R., Shah, S., Mathew, M.P., & Yarema, K.J. (2011) Exploring structure activity relationships of SCFA-hexosamine drug candidates by using non-hydrolysable ManNAc analogs. FDA/NIH Glycoscience Day, Bethesda, MD, June 15, 2011.
C79. Du, J., Espinoza, F.A., Tan, E., Bhattacharya, R., Shah, S., Mathew, M.P., & Yarema, K.J. (2011) Regulation of cancer cell adhesion via 3D electrospun nanofibrous scaffolds and metabolic oligosaccharide engineering. FDA/NIH Glycoscience Day, Bethesda, MD, June 15, 2011.
C80. Espinoza, F.A., Srinivas, R., Bhattacharya, R., Shah, S., Tan, E., Mathew, M.P., Du, J., & Yarema, K.J. (2011) Probing SCFA-hexosamine activity by computational docking studies. FDA/NIH Glycoscience Day, Bethesda, MD, June 15, 2011.
C81. Almaraz, R.T., Tian, Y., Bhattarcharya, R., Konstantopoulos, K., Zhang, H., & Yarema, K.J. (2011) Metabolic flux through the sialic acid pathway selectively controls the sialylation and activity of adhesion molecules involved in metastasis. Consortium for Functional Glycomics PI Meeting, Bethesda, MD, July 27-29, 2011.
C82. Krambeck, F.J., Brennun, S. V., Yarema, K. J., & Betenbaugh, M. J. (2011) Interpreting detailed mass spectrometry profiles and gene expression data using intracellular processing models. Consortium for Functional Glycomics PI Meeting, Bethesda, MD, July 27-29, 2011.
C83. Du, J., Kim, H.J., Zhang, A., Tan, E., Bhattacharya, R., & Yarema, K.J. (2011) Carbohydrate-based adhesion for tissue engineering and stem cell biology. 2011 Biomedical Engineering Society Meeting, Hartford, CT, October 12-15, 2011.
C84. von Bergen Granell, A.E., Aich, U., Akan, I., Palter, K.B., Yarema, K.J., Betenbaugh, M.J., Thornhill, W.B.,Recio-Pinto, E. (2011) Sialic Acid incorporation in CNS neurons of Drosophila melanogaster third instar larvae. Submitted to: Society of Neuroscience 2011 Meeting, Washington, DC, November 12-16, 2011.

D. Invited Lectures, Presentations, and Seminars:
D1. Yarema, K. J. (2001) Engineering glycosylation pathways in human cells, The Johns Hopkins University Glycobiology Interest Group, Baltimore, MD, December 4, 2001.
D2. Yarema, K. J. (2003) A systems biology approach to the study of sialic acid metabolism. Beckman Young Investigator Symposium, Newport Beach, CA., August 22, 2003.
D3. Yarema, K. J. (2003) Mutant forms of recombinant UDP-GlcNAc 2-epimerase/ManNAc. Hereditary Inclusion Body Myopathy Symposium, Lawton Chiles International Center at the National Institutes of Health, Bethesda, MD., November 21, 2003.
D4. Yarema, K. J. (2004) Monosaccharide-based modulation of sialic acid metabolism: Prospects for therapeutic applications. Invited Lecture, Food and Drug Administration, Bethesda, MD., April 22, 2004.
D5. Yarema, K. J. (2004) Chemical-biology methods to manipulate glycosylation: Applications and challenges for the metabolic Engineering of sialic acids. The 21st Century COE Young Scientist Network Symposium: Toward a Fusion of Bioscience and Nanotechnology, Hokkaido University, Sapporo, Japan, August 6, 2004.
D6. Yarema, K. J. (2004) A systems biology approach to the study of sialic acid metabolism, Beckman Young Investigator Symposium, Irvine, CA., August 23, 2004.
D7. Yarema, K. J. (2004) Cell surface oligosaccharide engineering: New directions for cancer therapy and tissue engineering. Invited Lecture, Osaka University, Osaka, Japan, September 21 2004.
D8. Yarema, K. J. (2004) Cell surface oligosaccharide engineering: New methods for cell adhesion, tissue engineering, and medicine. Invited Lecture, Osaka Prefecture University, Osaka, Japan, September 22, 2004.
D9. Yarema, K. J. (2004) Metabolic labeling of sialic Acid in neurons. Neuro2004: Glycobiology and the Plasticity of the Nervous System, Osaka, Japan, September 23, 2004.
D10. Yarema, K. J. (2004) Metabolic connections between sialic acid biosynthesis, human disease, and apoptosis, Johns Hopkins University Glycobiology Interest Group, Baltimore, MD, October 12, 2004.
D11. Yarema, K. J. (2005) Systems Biology Approach to the Study of Sialic Acid Metabolism: Is HIBM caused by Abnormal Sialic Acid Production? Beckman Young Investigator Symposium, Irvine, CA., August 26, 2005.
D12. Yarema, K. J. (2005) Connections between apoptosis and sialic acid metabolism: Application to new cancer therapies. GLYCO XVIII: The International Symposium on Glycoconjugates, Firenze, Italy, September 4, 2005.
D13. Yarema, K. J. (2005) Metabolic engineering of mammalian glycosylation with monosaccharide analogues. GLUPOR VI: 6th International Meeting of the Portuguese Carbohydrate Group | 3rd Iberian Carbohydrate Meeting, Coimbra, Portugal, September 11-15, 2005.
D14. Yarema, K. J. (2006) Sialic acid: A regulator of apoptosis, proliferation, and differentiation, Johns Hopkins University Glycobiology Interest Group, Baltimore, MD, February, 2006.
D15. Yarema, K. J. (2006) Connections between apoptosis and sialic acid metabolism: Application to new cancer therapies. The Interdisciplinary Translational Glycobiology Symposium, Arizona State University, Tempe, AZ., May 10-11, 2006.
D16. Yarema, K. J. (2006) Sialic acid engineering – A new method for controlling cell adhesion and stem cell fate. Department of Chemical Engineering Seminar Series, University of Maryland, Baltimore County, MD., May 15, 2006.
D17. Yarema, K. J. (2006) Sialic acid: A regulator of apoptosis, proliferation, and differentiation in cancer and stem cells. Symposium on Chemical Biology, National Cancer Institute, Frederick, MD., June 20, 2006.
D18. Yarema, K. J. (2006) A systems biology approach to the study of sialic acid metabolism. Beckman Young Investigators’ Symposium, Newport Beach, CA., August 25, 2006.
D19. Yarema, K. J. (2006) Systems biology of glycosylation. Chemistry/Biology Interface Symposium Series, University of Maryland, Baltimore County, MD., October 18, 2006.
D20. Yarema, K. J. (2007) Metabolic oligosaccharide engineering of sialic acid: Links between tissue engineering, stem cells, and cancer. Invited lecture for the Chemistry Department, University of Texas, Austin, January 26, 2007.
D21. Yarema, K. J. (2007) Metabolic oligosaccharide engineering: Developing applications ranging from control of stem cell fate to cancer therapies. Department of Biological-Chemistry and Chemistry Seminar, Grinnell College, Grinnell, IA, February 21, 2007.
D22. Yarema, K. J. (2007) Metabolic oligosaccharide engineering: Sialic acid based tools for tissue engineering and cancer. Department of Chemistry Seminar, Wayne State University, Detroit, MI., February 28, 2007.
D23. Yarema, K. J. (2007) Metabolic oligosaccharide engineering: Links between stem cells and cancer. Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA., April 12, 2007.
D24. Yarema, K. J. (2007) Chemical glycobiology: Control of pro-Invasive oncogenes in metastatic breast cancer cells with hexosamine analogs. Invited lecture at the 2007 Midwest Carbohydrate and Glycobiology Symposium, Ohio State University, Columbus, OH, October 6, 2007.
D25. Yarema, K. J. (2008) Combined effects of magnetic exposure, interleukin-6 signaling, and ganglioside regulation on stem cell differentiation. Department of Biology Seminar Series, The Johns Hopkins University, Baltimore, MD, March 6, 2008.
D26. Yarema, K. J. (2008) Metabolic glycoengineering: Steps towards the construction of an artificial stem cell niche. National Institutes of Health Glycosciences Day, Bethesda, MD, May 9, 2008.
D27. Yarema, K. J. (2008) Metabolic glycoengineering – developing new tools for the modification of glycans in living cells. Synthetic Biology Workshop, University of Groningen Centre for Synthetic Biology, The Netherlands, November 6-8, 2008.
D28. Yarema, K. J. (2009) Metabolic glycoengineering: Developing tools to modify cell surface chemistry in living cells. Department of Cell Biology Seminar, The Johns Hopkins School of Medicine, Baltimore, MD, February 5, 2009.
D29. Yarema, K. J. (2009) Sugar-based drug discovery by modulating gene expression: The hexosamine platform. Baltimore-Washington Glycobiology Interest Group, Baltimore, MD, February 10, 2009.
D30. Yarema, K. J. (2009) Sugar-based drug discovery: The hexosamine platform. Carbohydrates Gordon Research Conference, The Tilton School, Tilton, NH, June 18, 2009.
D31. Yarema, K. J. (2010) Metabolic Glycoengineering: A Research Overview. Department of Allergy and Clinical Immunology Seminar Series, Bayview Campus of The Johns Hopkins University, Baltimore, MD, March 10, 2010.
D32. Yarema, K. J. (2010) Hexosamine analogs: Discovering a template for drug development. NIH Glycoscience Day, Bethesda, MD, May 24, 2010.
D33. Yarema, K. J. (2010) Control of cell fate through metabolic sialic acd engineering. Sialoglyco 2010 Kongresshotel Potsam, Potsdam, Germany, August 22, 2010.