Our laboratory uses a multifaceted ‘glycoengineering’ approach that exploits the tools of chemical biology; synthetic chemistry; cellular biology and genetics; and materials science to study and manipulated glycosylation. Our overall goals are to better understand human disease while forwarding carbohydrate-based therapies by:

1. Developing glycoengineering tools and technology.

2. Applying metabolic glycoengineering (MGE) to treat disease (e.g., cancer and osteoarthritis).

3. Applying MGE to stem cell biology and regenerative medicine (coming soon).

4. Developing carbohydrate-based and targeting drugs that modulate cancer cell metabolism (coming soon).